Usp20 - SNV Details



 Gene Information 
Gene Name Usp20
Old Gene Names for Usp20 1700055m05rik , Ai467231
Gene Description ubiquitin specific peptidase 20 [Source:MGI Symbol;Acc:MGI:1921520]
Uniprot Name
CCDS Name
Gene GO
ubiquitin thiolesterase activity; perinuclear region of cytoplasm; regulation of G-protein coupled receptor protein signaling pathway; zinc ion binding; ubiquitin-dependent protein catabolic process; peptidase activity; protein K48-linked deubiquitination; cysteine-type endopeptidase activity; cellular_component; G-protein coupled receptor binding; proteolysis; protein deubiquitination; protein K63-linked deubiquitination; endocytosis
Homolog in other species USP20
Immgen Expression
MEDIAN(HIGH IN DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000026854
Chromosome 2
Coordinate 30,998,789     (Assembly: GRCm38)    
Ref Base T
Codon Change aTg/aAg
Var Base A
Zygosity Heterozygous
Read Depth 38
Allele Frequency
T:R0.42
A:V0.58
Amino Acid Position 1
Amino Acid Change M->K (Methionine -> Lysine)
Sample ID IGL01444
Median Base Quality 35.5
Backgrounds Balb/c:C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 39 Other Mutations

 Predictions 
Polyphen Score 0.93
Polyphen Prediction Possibly damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved