Gpr19 - SNV Details



 Gene Information 
Gene Name Gpr19
Gene Description G protein-coupled receptor 19 [Source:MGI Symbol;Acc:MGI:892973]
MGI phenotype Homozygous mutation of this gene results in increased anxiety-like behavior.
Uniprot Name
CCDS Name
Gene GO
integral to membrane; G-protein coupled receptor activity; G-protein coupled receptor signaling pathway; plasma membrane; biological_process; molecular_function
Homolog in other species GPR19
Omim http://omim.org/entry/602927
Immgen Expression
MEDIAN
Gnf Expression
HIGH(HIGHER IN IMM GROUP, NS GROUPS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000032641
Chromosome 6
Coordinate 134,870,321     (Assembly: GRCm38)    
Ref Base T
Codon Change cAc/cTc
Var Base A
Zygosity Heterozygous
Read Depth 13
Allele Frequency
T:R0.69
A:V0.31
Amino Acid Position 41
Amino Acid Change H->L (Histidine -> Leucine)
Sample ID IGL01373
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 43 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.49
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved