Il34 - SNV Details



 Gene Information 
Gene Name Il34
Old Gene Names for Il34 Ai593503 , 2010004a03rik
Gene Description interleukin 34 [Source:MGI Symbol;Acc:MGI:1923777]
Uniprot Name
CCDS Name
Gene GO
positive regulation of protein phosphorylation; inflammatory response; cytokine activity; macrophage colony-stimulating factor receptor binding; innate immune response; growth factor activity; extracellular space; positive regulation of cell proliferation
Homolog in other species IL34
Omim http://omim.org/entry/612081
Immgen Expression
MEDIAN(HIGHER IN DC.LC.SK)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031750
Chromosome 8
Coordinate 110,742,713     (Assembly: GRCm38)    
Ref Base T
Codon Change Aag/Gag
Var Base C
Zygosity Heterozygous
Read Depth 20
Allele Frequency
T:R0.50
C:V0.50
Amino Acid Position 157
Amino Acid Change K->E (Lysine -> Glutamic acid)
Sample ID IGL01420
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 56 Other Mutations

 Predictions 
Polyphen Score 0.96
Polyphen Prediction Probably damaging
Sift Score 0.01
Sift Prediction deleterious

 Availability Details 
Availability Progeny Cryopreserved