Fat3 - SNV Details



 Gene Information 
Gene Name Fat3
Old Gene Names for Fat3 Gm510 , 9430076a06rik , D430038h04rik , Gm1132
Gene Description FAT tumor suppressor homolog 3 (Drosophila) [Source:MGI Symbol;Acc:MGI:2444314]
Uniprot Name
CCDS Name
Gene GO
membrane; integral to membrane; homophilic cell adhesion; protein binding; plasma membrane; biological_process; calcium ion binding; multicellular organismal development
Homolog in other species FAT3
Omim http://omim.org/entry/612483
Immgen Expression
LOW
LOW
LOW
MEDIAN(LOWER IN TGD.VG5+.ACT.IEL)
MEDIAN(LOWER IN TGD.VG5+.ACT.IEL)
MEDIAN(LOWER IN TGD.VG5+.ACT.IEL)
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
MEDIAN
LOW
LOW
LOW
LOW
LOW
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
MEDIAN
MEDIAN(HIGH IN MACROPHAGES, OSTEOCLASTS)
LOW/MEDIAN
MEDIAN(HIGH IN NS GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000074505
Chromosome 9
Coordinate 16,378,023     (Assembly: GRCm38)    
Ref Base A
Codon Change aTa/aAa
Var Base T
Zygosity Heterozygous
Read Depth 45
Allele Frequency
A:R0.58
T:V0.42
Amino Acid Position 68
Amino Acid Change I->K (Isoleucine -> Lysine)
Sample ID IGL01407
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 37 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.65
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved