Pla2g4d - SNV Details



 Gene Information 
Gene Name Pla2g4d
Old Gene Names for Pla2g4d 2610311b01rik
Gene Description phospholipase A2, group IVD [Source:MGI Symbol;Acc:MGI:1925640]
Uniprot Name
CCDS Name
Gene GO
cytoplasmic vesicle membrane; phospholipase A2 activity; cytoplasm; metal ion binding; metabolic process; protein binding; cytosol; phospholipid catabolic process; phospholipase activity
Homolog in other species PLA2G4D
Omim http://omim.org/entry/612864
Immgen Expression
LOW
Gnf Expression
LOW/MEDIAN(HIGH IN FERTILIZEDEGG, OOCYTE)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000070719
Chromosome 2
Coordinate 120,266,823     (Assembly: GRCm38)    
Ref Base T
Codon Change aAt/aGt
Var Base C
Zygosity Heterozygous
Read Depth 36
Allele Frequency
T:R0.58
C:V0.42
Amino Acid Position 765
Amino Acid Change N->S (Asparagine -> Serine)
Sample ID IGL01405
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 
Polyphen Score 0.03
Polyphen Prediction Benign
Sift Score 0.01
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000092252:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Lysophospholipase, catalytic domain LysoPLipase_cat_dom IPR002642 ENSMUSP00000092252 Prosite_profiles 281
825 Description available Search pathways
Lysophospholipase, catalytic domain LysoPLipase_cat_dom IPR002642 ENSMUSP00000092252 Smart 263
766 Description available Search pathways
Acyl transferase/acyl hydrolase/lysophospholipase Acyl_Trfase/lysoPLipase IPR016035 ENSMUSP00000092252 Superfamily 287
816 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved