Fmo6 - SNV Details



 Gene Information 
Gene Name Fmo6
Gene Description flavin containing monooxygenase 6 [Source:MGI Symbol;Acc:MGI:2681841]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; oxidoreductase activity; intrinsic to endoplasmic reticulum membrane; N
N-dimethylaniline monooxygenase activity; NADP binding; flavin adenine dinucleotide binding
Homolog in other species FMO6P
Gnf Expression
LOW/MEDIAN(HIGH IN TESTIS, MEDIALOLFACTORYEPITHELIUM.MOE, VOMERALNASALORGAN.VMO, SEPTAL.ORGAN, SEPTUM.RESP.EPITH)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000095576
Chromosome 1
Coordinate 162,930,011     (Assembly: GRCm38)    
Ref Base T
Codon Change aaA/aaT
Var Base A
Zygosity Heterozygous
Read Depth 14
Allele Frequency
T:R0.64
A:V0.36
Amino Acid Position 64
Amino Acid Change K->N (Lysine -> Asparagine)
Sample ID IGL01392
Median Base Quality 39.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 33 Other Mutations

 Predictions 
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000136378:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Pyr_nucl-diS_OxRdtase_FAD/NAD IPR023753 ENSMUSP00000136378 Pfam 4
259 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved