Cd84 - SNV Details



 Gene Information 
Gene Name Cd84
Old Gene Names for Cd84 A130013d22rik
Gene Description CD84 antigen [Source:MGI Symbol;Acc:MGI:1336885]
MGI phenotype Mice homozygous for disruptions in this gene display defects in T follicular helper function, and germinal center formation.
Uniprot Name
CCDS Name
Gene GO
integral to membrane; receptor activity; cell adhesion; protein binding; plasma membrane
Homolog in other species CD84
Immgen Expression
MEDIAN(HIGH IN TGD.VG5+.ACT.IEL, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, DC.LC.SK, MYELOID GROUP)
Gnf Expression
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP, SPLEEN, TRACHEA, LUNG, ADIPOSETISSUE)
MEDIAN(HIGH IN IMM.G2, IMM.G3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000038147
Chromosome 1
Coordinate 171,886,370     (Assembly: GRCm38)    
Ref Base A
Codon Change Acc/Tcc
Var Base T
Zygosity Heterozygous
Read Depth 14
Allele Frequency
A:R0.64
T:V0.36
Amino Acid Position 312
Amino Acid Change T->S (Threonine -> Serine)
Sample ID IGL01371
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 32 Other Mutations

 Predictions 
Polyphen Score 0.11
Polyphen Prediction Benign
Sift Score 0.78
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved