Capn5,Omp - SNV Details



 Gene Information 
Gene Name Capn5 , Omp
Gene Description olfactory marker protein [Source:MGI Symbol;Acc:MGI:97436],calpain 5 [Source:MGI Symbol;Acc:MGI:1100859]
MGI phenotype Mice homozygous for one allele of this gene occasionally exhibit reduced viability but are usually normal. Homozygotes for another allele die as embryos.,Mice lacking both copies of the coding sequence for this gene exhibit no overt phenotype.
Uniprot Name
CCDS Name
Gene GO
luteinization; ovarian follicle development; intracellular; granulosa cell differentiation; protein binding; calcium-dependent cysteine-type endopeptidase activity; proteolysis
cytoplasm; signal transduction; neurogenesis; sensory perception of smell; neuronal cell body; nucleus; axon; cytosol; signal transducer activity
Homolog in other species OMP,CAPN5
Omim http://omim.org/entry/164340,http://omim.org/entry/602537
Immgen Expression
MEDIAN(HIGHER IN DC.LC.SK),MEDIAN(HIGH IN DC GROUP)
Gnf Expression
LOW/MEDIAN(HIGH IN TESTIS, MEDIALOLFACTORYEPITHELIUM.MOE, VOMERALNASALORGAN.VMO, SEPTAL.ORGAN, SEPTUM.RESP.EPITH),LOW/MEDIAN(HIGH IN DORSALROOTGANGLION, TRIGEMINAL)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000074006
Chromosome 7
Coordinate 98,145,282     (Assembly: GRCm38)    
Ref Base A
Codon Change aTc/aAc
Var Base T
Zygosity Heterozygous
Read Depth 54
Allele Frequency
A:R0.35
T:V0.65
Amino Acid Position 46
Amino Acid Change I->N (Isoleucine -> Asparagine)
Sample ID IGL01361
Median Base Quality 34
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 37 Other Mutations

 Predictions 
Polyphen Score 0.2
Polyphen Prediction Benign
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000095882:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Olfactory marker protein Olfactory_marker IPR009103 ENSMUSP00000095882 Pfam 11
162 Description available Search pathways
Olfactory marker protein Olfactory_marker IPR009103 ENSMUSP00000095882 Superfamily 2
163 Description available Search pathways

 Availability Details 
Availability Cryopreserved