Fbxw2 - SNV Details



 Gene Information 
Gene Name Fbxw2
Gene Description F-box and WD-40 domain protein 2 [Source:MGI Symbol;Acc:MGI:1353435]
Uniprot Name
CCDS Name
Gene GO
cytoplasm; protein binding
Homolog in other species FBXW2
Omim http://omim.org/entry/609071
Immgen Expression
HIGH
Gnf Expression
MEDIAN
MEDIAN(HIGH IN THYMUS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000035949
Chromosome 2
Coordinate 34,822,750     (Assembly: GRCm38)    
Ref Base T
Codon Change Act/Gct
Var Base C
Zygosity Heterozygous
Read Depth 23
Allele Frequency
T:R0.48
C:V0.52
Amino Acid Position 100
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL01359
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 48 Other Mutations

 Predictions 
Polyphen Score 0.06
Polyphen Prediction Benign
Sift Score 0.56
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000028220:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
F-box domain F-box_dom_cyclin-like IPR001810 ENSMUSP00000028220 Prosite_profiles 54
101 Description available Search pathways
F-box domain F-box_dom_cyclin-like IPR001810 ENSMUSP00000028220 Superfamily 52
137 Description available Search pathways

 Availability Details 
Availability Cryopreserved