Pik3c2g - SNV Details



 Gene Information 
Gene Name Pik3c2g
Old Gene Names for Pik3c2g C80387
Gene Description phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide [Source:MGI Symbol;Acc:MGI:1203730]
Uniprot Name
CCDS Name
Gene GO
kinase activity; cell communication; phosphatidylinositol phosphorylation; transferase activity
transferring phosphorus-containing groups; protein binding; binding; phosphatidylinositol binding; phosphotransferase activity
alcohol group as acceptor; phosphatidylinositol-mediated signaling; ATP binding
Homolog in other species PIK3C2G
Omim http://omim.org/entry/609001
Immgen Expression
LOW
Gnf Expression
MEDIAN(HIGH IN IMM.G2, SPLEEN)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000030228
Chromosome 6
Coordinate 139,852,857     (Assembly: GRCm38)    
Ref Base G
Codon Change gGc/gTc
Var Base T
Zygosity Heterozygous
Read Depth 45
Allele Frequency
G:R0.62
T:V0.38
Amino Acid Position 371
Amino Acid Change G->V (Glycine -> Valine)
Sample ID IGL01355
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 26 Other Mutations

 Predictions 
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000107499:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Protein kinase-like domain Kinase-like_dom IPR011009 ENSMUSP00000107499 Superfamily 280
638 Description available Search pathways

 Availability Details 
Availability Cryopreserved