Slc22a15 - SNV Details



 Gene Information 
Gene Name Slc22a15
Old Gene Names for Slc22a15 Bb219042 , 2610034p21rik , A530052i06rik
Gene Description solute carrier family 22 (organic anion/cation transporter), member 15 [Source:MGI Symbol;Acc:MGI:3607704]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; cellular_component; transmembrane transporter activity; transmembrane transport; biological_process; molecular_function
Homolog in other species SLC22A15
Omim http://omim.org/entry/608275
Immgen Expression
MEDIAN(HIGH IN GN.BM)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000033147
Chromosome 3
Coordinate 101,880,176     (Assembly: GRCm38)    
Ref Base A
Codon Change agT/agG
Var Base C
Zygosity Heterozygous
Read Depth 69
Allele Frequency
A:R0.62
C:V0.38
Amino Acid Position 259
Amino Acid Change S->R (Serine -> Arginine)
Sample ID IGL01345
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 23 Other Mutations

 Predictions 
Sift Score 0.55
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000102541:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Major facilitator superfamily MFS IPR011701 ENSMUSP00000102541 Pfam 111
450 Description available Search pathways
General substrate transporter Sub_transporter IPR005828 ENSMUSP00000102541 Pfam 107
491 Description available Search pathways
Major facilitator superfamily domain MFS_dom IPR020846 ENSMUSP00000102541 Prosite_profiles 37
486 Description available Search pathways

 Availability Details 
Availability Cryopreserved