Oc90 - SNV Details

 Gene Information 
Gene Name Oc90
Old Gene Names for Oc90 Pla2ll
Gene Description otoconin 90 [Source:MGI Symbol;Acc:MGI:1313269]
MGI phenotype Mice homozygous for a null allele exhibit reduced, enlarged, and loose otoliths, and thin cupula, saccule, utricle and tectorial membranes.
Uniprot Name
Gene GO
phospholipase A2 activity; proteinaceous extracellular matrix; structural molecule activity; lipid catabolic process; calcium ion binding; phospholipid metabolic process
Homolog in other species OC90
Omim http://omim.org/entry/601658
Immgen Expression
Gnf Expression
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000015001
Chromosome 15
Coordinate 65,889,591     (Assembly: GRCm38)    
Ref Base T
Codon Change Act/Gct
Var Base C
Zygosity Heterozygous
Read Depth 26
Allele Frequency
Amino Acid Position 193
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL01343
Median Base Quality 36
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 57 Other Mutations

Polyphen Score 0.01
Polyphen Prediction Benign
Sift Score 0.29
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Protein domains 
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Phospholipase A2 domain PLipase_A2_dom IPR016090 ENSMUSP00000062865 Superfamily 74
197 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved