Cand2 - SNV Details



 Gene Information 
Gene Name Cand2
Old Gene Names for Cand2 2210404g23rik
Gene Description cullin-associated and neddylation-dissociated 2 (putative) [Source:MGI Symbol;Acc:MGI:1914338]
Uniprot Name
CCDS Name
Gene GO
transcription
DNA-dependent; intracellular; protein binding; binding; nucleus; TBP-class protein binding; regulation of transcription
DNA-dependent; biological_process
Homolog in other species CAND2
Immgen Expression
MEDIAN(HIGHER IN PROB.FRBC.FL, PREB.FRD.FL, T.DPSM.TH, TGD.TH)
Gnf Expression
MEDIAN(HIGH IN C2C12, HEART, SKELETALMUSCLE)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000030319
Chromosome 6
Coordinate 115,782,794     (Assembly: GRCm38)    
Ref Base T
Codon Change aTc/aCc
Var Base C
Zygosity Heterozygous
Read Depth 35
Allele Frequency
T:R0.46
C:V0.54
Amino Acid Position 142
Amino Acid Change I->T (Isoleucine -> Threonine)
Sample ID IGL01329
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 43 Other Mutations

 Predictions 
Polyphen Score 0.99
Polyphen Prediction Probably damaging
Sift Score 0.01
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000075377:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Armadillo-type fold ARM-type_fold IPR016024 ENSMUSP00000075377 Superfamily 6
1214 Description available Search pathways

 Availability Details 
Availability Line Propagating , Progeny Cryopreserved , Cryopreserved