Zfhx4 - SNV Details



 Gene Information 
Gene Name Zfhx4
Old Gene Names for Zfhx4 C130041o22rik , Zfh4
Gene Description zinc finger homeodomain 4 [Source:MGI Symbol;Acc:MGI:2137668]
Uniprot Name
CCDS Name
Gene GO
sequence-specific DNA binding; cytoskeleton organization; intracellular; zinc ion binding; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; cellular_component; regulation of transcription
DNA-dependent; nucleic acid binding; biological_process; actin binding
Homolog in other species ZFHX4
Omim http://omim.org/entry/606940
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
Gnf Expression
LOW/MEDIAN(HIGH IN C2C12, M1)
MEDIAN(HIGH IN M1)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000025255
Chromosome 3
Coordinate 5,244,284     (Assembly: GRCm38)    
Ref Base C
Codon Change Ctg/Atg
Var Base A
Zygosity Heterozygous
Read Depth 78
Allele Frequency
C:R0.53
A:V0.47
Amino Acid Position 857
Amino Acid Change L->M (Leucine -> Methionine)
Sample ID IGL01328
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 57 Other Mutations

 Predictions 
Polyphen Score 0.99
Polyphen Prediction Probably damaging
Sift Score 0.36
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved