Tnrc6b - SNV Details



 Gene Information 
Gene Name Tnrc6b
Old Gene Names for Tnrc6b 2700090m07rik , A730065c02rik , Ai848765 , D230019k20rik
Gene Description trinucleotide repeat containing 6b [Source:MGI Symbol;Acc:MGI:2443730]
Uniprot Name
CCDS Name
Gene GO
RNA binding; regulation of translation; gene silencing by RNA; protein binding; cytoplasmic mRNA processing body; cellular_component; nucleotide binding; biological_process; molecular_function
Homolog in other species TNRC6B
Omim http://omim.org/entry/610740
Immgen Expression
HIGH
Gnf Expression
MEDIAN
MEDIAN/HIGH(LOWER IN PANCREAS, KIDNEY, LIVER, BROWNFAT, SPLEEN, IMM.G2, THYROID, GI GROUP)
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000047888
Chromosome 15
Coordinate 80,923,578     (Assembly: GRCm38)    
Ref Base G
Codon Change cGc/cAc
Var Base A
Zygosity Heterozygous
Read Depth 65
Allele Frequency
G:R0.46
A:V0.54
Amino Acid Position 1577
Amino Acid Change R->H (Arginine -> Histidine)
Sample ID IGL01312
Median Base Quality 34
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 21 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Progeny Cryopreserved