Gbp4 - SNV Details



 Gene Information 
Gene Name Gbp4
Gene Description guanylate binding protein 4 [Source:MGI Symbol;Acc:MGI:97072]
Uniprot Name
CCDS Name
Gene GO
negative regulation of protein import into nucleus; negative regulation of protein phosphorylation; negative regulation of interferon-alpha production; GTPase activity; regulation of defense response to virus; protein binding; cellular_component; GTP binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of protein ubiquitination; cellular response to interferon-gamma
Homolog in other species GBP6
Omim http://omim.org/entry/612466
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, ABT GROUP, TACTIVATION GROUP, NK GROUP,MO.6C+II-.LN, B.FO.SP, B.MZ.SP, B1A.PC)
Gnf Expression
MEDIAN(HIGH IN IMM.G1, IMM.G3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000079363
Chromosome 5
Coordinate 105,137,021     (Assembly: GRCm38)    
Ref Base T
Codon Change Atg/Gtg
Var Base C
Zygosity Heterozygous
Read Depth 85
Allele Frequency
T:R0.51
C:V0.49
Amino Acid Position 1
Amino Acid Change M->V (Methionine -> Valine)
Sample ID IGL01307
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Sift Score 0.09
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved