Nsun7 - SNV Details



 Gene Information 
Gene Name Nsun7
Old Gene Names for Nsun7 4921525l17rik
Gene Description NOL1/NOP2/Sun domain family, member 7 [Source:MGI Symbol;Acc:MGI:1918168]
MGI phenotype Males homozygous for an ENU-induced mutation are either infertile or subfertile. Mutant sperm exhibit poor progressive motility linked to rigidity of the flagellar midpiece and abnormal electron density patterns in the mitochondrial sheath.
Uniprot Name
CCDS Name
Gene GO
methyltransferase activity
Homolog in other species NSUN7
Immgen Expression
LOW
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000029206
Chromosome 5
Coordinate 66,283,601     (Assembly: GRCm38)    
Ref Base T
Codon Change aTa/aCa
Var Base C
Zygosity Heterozygous
Read Depth 19
Allele Frequency
T:R0.53
C:V0.47
Amino Acid Position 355
Amino Acid Change I->T (Isoleucine -> Threonine)
Sample ID IGL01013
Median Base Quality 38
Backgrounds Balb/C,C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 45 Other Mutations

 Predictions 
Polyphen Score 0.87
Polyphen Prediction Possibly damaging
Sift Score 0.01
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved