Drosha - SNV Details



 Gene Information 
Gene Name Drosha
Old Gene Names for Drosha 1110013a17rik , Ai874853 , Etohi2 , Rnasen
Gene Description drosha, ribonuclease type III [Source:MGI Symbol;Acc:MGI:1261425]
Uniprot Name
CCDS Name
Gene GO
ribosome biogenesis; ribonuclease III activity; RNA binding; miRNA metabolic process; metal ion binding; intracellular; regulation of gene expression; protein binding; pre-miRNA processing; rRNA catabolic process; double-stranded RNA binding; endoribonuclease activity; nucleolus; RNA processing
Homolog in other species DROSHA
Omim http://omim.org/entry/608828
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000022191
Chromosome 15
Coordinate 12,827,289     (Assembly: GRCm38)    
Ref Base C
Codon Change aCg/aTg
Var Base T
Zygosity Heterozygous
Read Depth 61
Allele Frequency
C:R0.59
T:V0.41
Amino Acid Position 5
Amino Acid Change T->M (Threonine -> Methionine)
Sample ID IGL01010
Median Base Quality 37
Backgrounds Balb/C,C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 27 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Unknown
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved