Havcr2 - SNV Details



 Gene Information 
Gene Name Havcr2
Old Gene Names for Havcr2 Timd3
Gene Description hepatitis A virus cellular receptor 2 [Source:MGI Symbol;Acc:MGI:2159682]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; protein binding
Homolog in other species HAVCR2
Immgen Expression
LOW(HIGH IN MYELOID GOUP, DC8+.TH, DC.LC.SK)
Gnf Expression
MEDIAN
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000020399
Chromosome 11
Coordinate 46,456,427     (Assembly: GRCm38)    
Ref Base A
Codon Change tAt/tGt
Var Base G
Zygosity Heterozygous
Read Depth 21
Allele Frequency
A:R0.48
G:V0.52
Amino Acid Position 77
Amino Acid Change Y->C (Tyrosine -> Cysteine)
Sample ID IGL01122
Median Base Quality 40
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 38 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0.01
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000020668:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Immunoglobulin subtype Ig_sub IPR003599 ENSMUSP00000020668 Smart 23
131 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved