Srrt - SNV Details



 Gene Information 
Gene Name Srrt
Old Gene Names for Srrt 2810019g02rik , Ars2
Gene Description serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]
MGI phenotype Mice homozygous for a null allele display embryonic lethality before somite formation, increased apoptosis, and when cultured most fail to hatch from the zona pellucida.
Uniprot Name
CCDS Name
Gene GO
nucleoplasm; primary miRNA processing; transcription
DNA-dependent; cytoplasm; cell proliferation; DNA binding; protein binding; neuronal stem cell maintenance; regulation of transcription
DNA-dependent
Homolog in other species SRRT
Omim http://omim.org/entry/614469
Immgen Expression
HIGH(HIGHER IN B.GC.SP, PROB.FRBC.FL, PREB.FRD.FL, TGD GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037364
Chromosome 5
Coordinate 137,296,307     (Assembly: GRCm38)    
Ref Base C
Codon Change gGc/gTc
Var Base A
Zygosity Heterozygous
Read Depth 46
Allele Frequency
C:R0.54
A:V0.44
Amino Acid Position 779
Amino Acid Change G->V (Glycine -> Valine)
Sample ID IGL01062
Median Base Quality 35
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 44 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.08
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved