Rab32 - SNV Details



 Gene Information 
Gene Name Rab32
Old Gene Names for Rab32 2810011a17rik , Au022057
Gene Description RAB32, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1915094]
Uniprot Name
CCDS Name
Gene GO
mitochondrion; GTP catabolic process; membrane; cytoplasm; signal transduction; nucleocytoplasmic transport; protein transport; intracellular; GTPase activity; small GTPase mediated signal transduction; intracellular protein transport; nucleus; GTP binding
Homolog in other species RAB32
Omim http://omim.org/entry/612906
Immgen Expression
LOW(HIGH IN MYELOID GROUP, DC GROUP, TGD.SP)
Gnf Expression
MEDIAN(HIGH IN FERTILIZEDEGG, OOCYTE, IMM.G3, OSTEO GROUP, C2C12, UMBLICALCORD, NIH.3T3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000019832
Chromosome 10
Coordinate 10,557,874     (Assembly: GRCm38)    
Ref Base A
Codon Change cTc/cCc
Var Base G
Zygosity Heterozygous
Read Depth 15
Allele Frequency
A:R0.67
G:V0.33
Amino Acid Position 72
Amino Acid Change L->P (Leucine -> Proline)
Sample ID IGL01061
Median Base Quality 33
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Polyphen Score 0.97
Polyphen Prediction Probably damaging
Sift Score 0.1
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000019974:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Ran GTPase Ran_GTPase IPR002041 ENSMUSP00000019974 Smart 29
220 Description available Search pathways
Small GTPase superfamily Small_GTPase IPR001806 ENSMUSP00000019974 Pfam 25
190 Description available Search pathways
Mitochondrial Rho-like MIRO-like IPR013684 ENSMUSP00000019974 Pfam 25
144 Description available Search pathways
P-loop containing nucleoside triphosphate hydrolase P-loop_NTPase IPR027417 ENSMUSP00000019974 Superfamily 19
223 Description available Search pathways
Small GTPase superfamily, Ras type Small_GTPase_Ras IPR020849 ENSMUSP00000019974 Smart 21
193 Description available Search pathways
Small GTP-binding protein domain Small_GTP-bd_dom IPR005225 ENSMUSP00000019974 TIGRfam 24
186 Description available Search pathways
Small GTPase superfamily, Rho type Small_GTPase_Rho IPR003578 ENSMUSP00000019974 Smart 26
189 Description available Search pathways
Small GTPase superfamily, Rab type Small_GTPase_Rab_type IPR003579 ENSMUSP00000019974 Smart 24
193 Description available Search pathways
Small GTPase superfamily, ARF/SAR type Small_GTPase_ARF/SAR IPR006689 ENSMUSP00000019974 Pfam 21
153 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved