Lrrc66 - SNV Details



 Gene Information 
Gene Name Lrrc66
Old Gene Names for Lrrc66 Bc031901
Gene Description leucine rich repeat containing 66 [Source:MGI Symbol;Acc:MGI:2387634]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; protein binding; cellular_component; biological_process; molecular_function
Homolog in other species LRRC66
Immgen Expression
MEDIAN(HIGHER IN DC.LC.SK)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000067206
Chromosome 5
Coordinate 73,615,499     (Assembly: GRCm38)    
Ref Base T
Codon Change Aaa/Gaa
Var Base C
Zygosity Heterozygous
Read Depth 33
Allele Frequency
T:R0.61
C:V0.39
Amino Acid Position 209
Amino Acid Change K->E (Lysine -> Glutamic acid)
Sample ID IGL01061
Median Base Quality 37
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Polyphen Score 0.99
Polyphen Prediction Probably damaging
Sift Score 0.01
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000084423:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Leucine-rich repeat, typical subtype Leu-rich_rpt_typical-subtyp IPR003591 ENSMUSP00000084423 Smart 187
210 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved