Ddo - SNV Details



 Gene Information 
Gene Name Ddo
Old Gene Names for Ddo 5330420d20rik , Ai467244 , 5730402c02rik
Gene Description D-aspartate oxidase [Source:MGI Symbol;Acc:MGI:1925528]
MGI phenotype Homozygous null mice are viable and fertile, but can display impaired male copulation, decreased autogrooming, increased body weight, and increased D-aspartate levels, depending on the mutant allele.
Uniprot Name
CCDS Name
Gene GO
aspartate metabolic process
binding
grooming behavior
hormone metabolic process
insemination
oxidoreductase activity
Homolog in other species DDO
Immgen Expression
LOW
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000063428
Chromosome 10
Coordinate 40,647,554     (Assembly: GRCm38)    
Ref Base T
Codon Change gTc/gCc
Var Base C
Zygosity Heterozygous
Read Depth 73
Allele Frequency
T:0.38
C:0.62
Amino Acid Position 180
Amino Acid Change V->A (Valine -> Alanine)
Sample ID IGL00902
Median Base Quality 37
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 42 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000019977:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
FAD dependent oxidoreductase FAD-dep_OxRdtase IPR006076 ENSMUSP00000019977 Pfam 6
319 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved