Dok3 - SNV Details



 Gene Information 
Gene Name Dok3
Old Gene Names for Dok3 Ai450713
Gene Description docking protein 3 [Source:MGI Symbol;Acc:MGI:1351490]
MGI phenotype Mice homozygous for a knock-out allele exhibit increased incidence of lung adenocarcinomas.
Uniprot Name
CCDS Name
Gene GO
insulin receptor binding; cytoplasm; protein binding; Ras protein signal transduction; plasma membrane
Homolog in other species DOK3
Omim http://omim.org/entry/611435
Immgen Expression
MEDIAN/HIGH(HIGH IN BCELL GROUP, MYELOID GROUP, DC GROUP)
Gnf Expression
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000035711
Chromosome 13
Coordinate 55,524,231     (Assembly: GRCm38)    
Ref Base G
Var Base T
Zygosity Heterozygous
Read Depth 12
Allele Frequency
G:R0.33
T:V0.67
Amino Acid Change Y->Stop (Tyrosine -> Stop)
Sample ID IGL03410
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 
Polyphen Prediction N/A

 Availability Details 
Availability Cryopreserved