Trpm2 - SNV Details

 Gene Information 
Gene Name Trpm2
Old Gene Names for Trpm2 9830168k16rik , C79133 , Trrp7
Gene Description transient receptor potential cation channel, subfamily M, member 2 [Source:MGI Symbol;Acc:MGI:1351901]
MGI phenotype Mice homozygous for a knock-out allele display impaired reactive oxygen species (ROS)-induced chemokine production in monocytes, and reduced neutrophil infiltration and ulceration in a dextran sulfate sodium-induced colitis inflammation model.
Uniprot Name
Gene GO
manganese ion transmembrane transport; membrane; response to hydroperoxide; hydrolase activity; sodium ion transmembrane transport; sodium channel activity; ADP-ribose diphosphatase activity; metabolic process; integral component of membrane; ion channel activity; ion transport; transmembrane transport; manganese ion transmembrane transporter activity; plasma membrane; calcium channel activity; calcium ion transmembrane transport; manganese ion transport
Homolog in other species TRPM2
Immgen Expression
Gnf Expression
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000009292
Chromosome 10
Coordinate 77,966,072     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 31
Allele Frequency
Amino Acid Change Disrupted splicing
Splice Position 5
Sample ID IGL03405
Median Base Quality 41
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 37 Other Mutations


 Availability Details 
Availability Cryopreserved