Srpk2 - SNV Details



 Gene Information 
Gene Name Srpk2
Old Gene Names for Srpk2 Wbp6 , Aw226533 , Aw492537 , Aw547358
Gene Description serine/arginine-rich protein specific kinase 2 [Source:MGI Symbol;Acc:MGI:1201408]
MGI phenotype Mice homozygous for a targeted allele exhibit normal phenotype.
Uniprot Name
CCDS Name
Gene GO
cell differentiation; intracellular signal transduction; protein kinase activity; cytoplasm; RNA splicing; positive regulation of viral genome replication; positive regulation of neuron apoptotic process; poly(A) RNA binding; negative regulation of viral genome replication; 14-3-3 protein binding; transferase activity
transferring phosphorus-containing groups; angiogenesis; protein binding; nucleus; magnesium ion binding; protein phosphorylation; protein tyrosine kinase activity; positive regulation of cell cycle; ATP binding; nuclear speck organization; nucleolus; spliceosomal complex assembly; positive regulation of cell proliferation; protein serine/threonine kinase activity; positive regulation of gene expression
Homolog in other species SRPK2
Immgen Expression
MEDIAN(LOW IN PROB.FRBC.FL, DC8+.TH, DC.LC.SK)
Gnf Expression
MEDIAN/HIGH(LOWER IN PANCREAS, KIDNEY, LIVER, BROWNFAT, SPLEEN, IMM.G2, THYROID, GI GROUP)
MEDIAN(HIGH IN NS GROUP)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000062604
Chromosome 5
Coordinate 23,524,618     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 22
Allele Frequency
T:R0.55
C:V0.46
Amino Acid Change Disrupted splicing
Splice Position 3
Sample ID IGL03115
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 52 Other Mutations

 Predictions 

 Availability Details 
Availability Cryopreserved