Srgap1 - SNV Details



 Gene Information 
Gene Name Srgap1
Gene Description SLIT-ROBO Rho GTPase activating protein 1 [Source:MGI Symbol;Acc:MGI:2152936]
Uniprot Name
CCDS Name
Gene GO
signal transduction; positive regulation of Rho GTPase activity; intracellular; Rho protein signal transduction; protein binding; cell migration; Rho GTPase binding; Rho GTPase activator activity
Homolog in other species SRGAP1
Omim http://omim.org/entry/606523
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000020121
Chromosome 10
Coordinate 121,825,693     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 50
Allele Frequency
T:R0.54
C:V0.46
Amino Acid Change D->G (Aspartic acid -> Glycine)
Sample ID IGL03088
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 77 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved