Dclk1 - SNV Details



 Gene Information 
Gene Name Dclk1
Old Gene Names for Dclk1 Dcamkl1 , 1700113d08rik , 2810480f11rik , Ai836758
Gene Description doublecortin-like kinase 1 [Source:MGI Symbol;Acc:MGI:1330861]
Uniprot Name
CCDS Name
Gene GO
dendrite morphogenesis; axon extension; intracellular signal transduction; protein kinase activity; kinase activity; axonogenesis; response to virus; transferase activity
transferring phosphorus-containing groups; phosphorylation; central nervous system projection neuron axonogenesis; neuron migration; protein phosphorylation; protein tyrosine kinase activity; ATP binding; forebrain development; protein serine/threonine kinase activity; brain development
Homolog in other species DCLK1
Omim http://omim.org/entry/604742
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000027797
Chromosome 3
Coordinate 55,247,367     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 51
Allele Frequency
G:R0.45
A:V0.55
Amino Acid Change V->M (Valine -> Methionine)
Sample ID IGL03086
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 33 Other Mutations

 Predictions 
Polyphen Score 0.39
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved