Ddx60 - SNV Details



 Gene Information 
Gene Name Ddx60
Old Gene Names for Ddx60 Bc013672
Gene Description DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Source:MGI Symbol;Acc:MGI:2384570]
Uniprot Name
CCDS Name
Gene GO
helicase activity; RNA binding; cytoplasm; response to virus; metabolic process; protein binding; double-stranded DNA binding; single-stranded RNA binding; intermediate filament cytoskeleton; nucleic acid binding; defense response to virus; double-stranded RNA binding; ATP binding; positive regulation of RIG-I signaling pathway; positive regulation of MDA-5 signaling pathway
Homolog in other species DDX60
Omim http://omim.org/entry/613974
Immgen Expression
MEDIAN(HIGH IN GN.BM, B.FO.SP, B.MZ.SP, B1A.PC, NK GROUP, ABT GROUP, TACTIVATION GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037921
Chromosome 8
Coordinate 61,956,121     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 30
Allele Frequency
A:R0.50
T:V0.50
Amino Acid Change D->V (Aspartic acid -> Valine)
Sample ID IGL03295
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 32 Other Mutations

 Predictions 
Polyphen Score 0.04
Polyphen Prediction Benign

 Availability Details 
Availability Progeny Cryopreserved