Ppp2cb - SNV Details



 Gene Information 
Gene Name Ppp2cb
Old Gene Names for Ppp2cb Ai115466 , D8ertd766e
Gene Description protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform [Source:MGI Symbol;Acc:MGI:1321161]
Uniprot Name
CCDS Name
Gene GO
response to endoplasmic reticulum stress; proteasome-mediated ubiquitin-dependent protein catabolic process; protein dephosphorylation; chromosome
centromeric region; hydrolase activity; cytoplasm; phosphoprotein phosphatase activity; metal ion binding; protein C-terminus binding; regulation of gene expression; apoptotic mitochondrial changes; protein binding; protein phosphatase type 2A complex; nucleus; extracellular vesicular exosome; spindle pole; response to antibiotic; protein serine/threonine phosphatase activity; response to hydrogen peroxide; negative regulation of Ras protein signal transduction
Homolog in other species PPP2CB
Omim http://omim.org/entry/176916
Immgen Expression
HIGH(HIGHER IN MYELOID GROUP, DC GROUP, TGD GROUP)
Gnf Expression
MEDIAN/HIGH(LOWER IN TESTIS, FERTILIZEDEGG, OOCYTE, KIDNEY, LIVER, SPLEEN, THYROID)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000009630
Chromosome 8
Coordinate 33,610,651     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 29
Allele Frequency
A:R0.48
T:V0.52
Amino Acid Change Disrupted splicing
Splice Position 4
Sample ID IGL03251
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 31 Other Mutations

 Predictions 

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved