Pa2g4 - SNV Details



 Gene Information 
Gene Name Pa2g4
Old Gene Names for Pa2g4 Aa672939 , Plfap
Gene Description proliferation-associated 2G4 [Source:MGI Symbol;Acc:MGI:894684]
MGI phenotype Mice homozygous for a null allele exhibit decreased body size and weight during early adulthood and produce smaller than normal litters.
Uniprot Name
CCDS Name
Gene GO
RNA binding; negative regulation of transcription
DNA-templated; hydrolase activity; cytoplasm; regulation of translation; DNA binding; sequence-specific DNA binding transcription factor activity; metabolic process; nucleus; ribonucleoprotein complex; rRNA processing; nucleolus; transcription
DNA-templated
Homolog in other species PA2G4
Omim http://omim.org/entry/602145
Immgen Expression
MEDIAN/HIGH(LOW IN MYELOID GROUP, HIGH IN BCELL GROUP, ABT GROUP)
Gnf Expression
MEDIAN(HIGH IN EMB GROUP, PLACENTA)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000025364
Chromosome 10
Coordinate 128,565,778     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 28
Allele Frequency
A:R0.57
G:V0.36
Amino Acid Change V->A (Valine -> Alanine)
Sample ID IGL03198
Median Base Quality 33
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 34 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved