Adam6a - SNV Details



 Gene Information 
Gene Name Adam6a
Old Gene Names for Adam6a Adam6
Gene Description a disintegrin and metallopeptidase domain 6A [Source:MGI Symbol;Acc:MGI:2676316]
Uniprot Name
CCDS Name
Gene GO
zinc ion binding; protein binding; cell surface; proteolysis; integrin-mediated signaling pathway; metalloendopeptidase activity; biological_process; molecular_function
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000043945
Chromosome 12
Coordinate 113,545,524     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 83
Allele Frequency
A:R0.64
T:V0.36
Amino Acid Change T->S (Threonine -> Serine)
Sample ID IGL03146
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 43 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved