Tmem8 - SNV Details



 Gene Information 
Gene Name Tmem8
Old Gene Names for Tmem8 Aw490096
Gene Description transmembrane protein 8 (five membrane-spanning domains) [Source:MGI Symbol;Acc:MGI:1926283]
Uniprot Name
CCDS Name
Gene GO
lysosomal membrane; cell adhesion; protein binding; integral component of plasma membrane; biological_process; molecular_function
Homolog in other species TMEM8A
Immgen Expression
MEDIAN(HIGHER IN MYELOID GROUP, TGD.VG5+.ACT.IEL)
Gnf Expression
LOW/MEDIAN(HIGH IN KIDNEY, LIVER, BLASTOCYSTS, GI GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000024180
Chromosome 17
Coordinate 26,116,834     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 42
Allele Frequency
G:R0.50
A:V0.50
Amino Acid Change R->Q (Arginine -> Glutamine)
Sample ID IGL03124
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 45 Other Mutations

 Predictions 
Polyphen Score 0.97
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved