Cd180 - SNV Details



 Gene Information 
Gene Name Cd180
Old Gene Names for Cd180 Ly78
Gene Description CD180 antigen [Source:MGI Symbol;Acc:MGI:1194924]
MGI phenotype Mice homozygous for a null mutation showed impaired proliferative and humoral immune responses of B cells to lipopolysaccharides.
Uniprot Name
CCDS Name
Gene GO
B cell proliferation involved in immune response; integral component of membrane; inflammatory response; cellular response to lipopolysaccharide; innate immune response; plasma membrane; positive regulation of lipopolysaccharide-mediated signaling pathway
Homolog in other species CD180
Omim http://omim.org/entry/602226
Immgen Expression
LOW(HIGH IN BCELL GROUP, MYELOID GROUP, DC GROUP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000021624
Chromosome 13
Coordinate 102,705,027     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 40
Allele Frequency
A:R0.50
G:V0.50
Amino Acid Change S->G (Serine -> Glycine)
Sample ID IGL03031
Median Base Quality 37.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 52 Other Mutations

 Predictions 
Polyphen Score 0.07
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved