Tead2 - SNV Details



 Gene Information 
Gene Name Tead2
Old Gene Names for Tead2 Etdf
Gene Description TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904]
MGI phenotype Mice homozygous for a functionally null allele of this gene exhibit no gross abnormalities and are fertile.
Uniprot Name
CCDS Name
Gene GO
embryonic heart tube morphogenesis; transcription from RNA polymerase II promoter; regulation of transcription
DNA-templated; positive regulation of transcription from RNA polymerase II promoter; lateral mesoderm development; vasculogenesis; DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; negative regulation of cell death; protein binding; paraxial mesoderm development; nucleus; neural tube closure; hippo signaling; notochord development; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
Homolog in other species TEAD2
Omim http://omim.org/entry/601729
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
Gnf Expression
MEDIAN(HIGH IN EMB GROUP, PLACENTA)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000030796
Chromosome 7
Coordinate 45,220,434     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 144
Allele Frequency
T:R0.52
C:V0.48
Amino Acid Change Disrupted splicing
Splice Position 4
Sample ID IGL02939
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 

 Availability Details 
Availability Progeny Cryopreserved