Ap1ar - SNV Details

 Gene Information 
Gene Name Ap1ar
Old Gene Names for Ap1ar Bc002199 , Aa407621 , C78909
Gene Description adaptor-related protein complex 1 associated regulatory protein [Source:MGI Symbol;Acc:MGI:2384822]
Uniprot Name
Gene GO
negative regulation of substrate adhesion-dependent cell spreading; negative regulation of receptor recycling; cytoplasm; AP-1 adaptor complex binding; negative regulation of cell motility; regulation of Arp2/3 complex-mediated actin nucleation; endosome; transport vesicle; cellular protein localization; vesicle targeting
trans-Golgi to endosome; nucleolus; Golgi apparatus; kinesin binding
Homolog in other species AP1AR
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000074238
Chromosome 3
Coordinate 127,808,543     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 33
Allele Frequency
Amino Acid Change E->G (Glutamic acid -> Glycine)
Sample ID IGL02887
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 87 Other Mutations

Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved