Naip2 - SNV Details



 Gene Information 
Gene Name Naip2
Old Gene Names for Naip2 Birc1b , Naip-rs6
Gene Description NLR family, apoptosis inhibitory protein 2 [Source:MGI Symbol;Acc:MGI:1298226]
Uniprot Name
CCDS Name
Gene GO
cellular response to estrogen stimulus; apoptotic process; metal ion binding; pyroptosis; inflammatory response; defense response to bacterium; detection of bacterium; IPAF inflammasome complex; innate immune response; ATP binding
Homolog in other species NAIP
Immgen Expression
LOW(HIGH IN MYELOID GROUP, DC GROUP, TGD.SP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000078945
Chromosome 13
Coordinate 100,161,512     (Assembly: GRCm38)    
Ref Base T
Var Base G
Zygosity Heterozygous
Read Depth 66
Allele Frequency
T:R0.47
G:V0.53
Amino Acid Change Y->S (Tyrosine -> Serine)
Sample ID IGL02887
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 87 Other Mutations

 Predictions 
Polyphen Score 0.7
Polyphen Prediction Possibly damaging

 Availability Details 
Availability Progeny Cryopreserved