Cldn8 - SNV Details



 Gene Information 
Gene Name Cldn8
Old Gene Names for Cldn8 Ai648025
Gene Description claudin 8 [Source:MGI Symbol;Acc:MGI:1859286]
Uniprot Name
CCDS Name
Gene GO
tight junction; endoplasmic reticulum; protein binding; integral component of membrane; structural molecule activity; plasma membrane; identical protein binding; basolateral plasma membrane; calcium-independent cell-cell adhesion
Homolog in other species CLDN8
Omim http://omim.org/entry/611231
Immgen Expression
LOW
Gnf Expression
MEDIAN(HIGH IN KIDNEY, LIVER, IMM GROUP, OSTEO GROUP, PROSTATE)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000050520
Chromosome 16
Coordinate 88,562,383     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 27
Allele Frequency
A:R0.37
T:V0.63
Amino Acid Change I->K (Isoleucine -> Lysine)
Sample ID IGL02888
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Polyphen Score 0.01
Polyphen Prediction Benign

 Availability Details 
Availability Progeny Cryopreserved