Wee1 - SNV Details



 Gene Information 
Gene Name Wee1
Gene Description WEE 1 homolog 1 (S. pombe) [Source:MGI Symbol;Acc:MGI:103075]
Uniprot Name
CCDS Name
Gene GO
nucleoplasm; protein kinase activity; mitotic nuclear division; cytoplasm; peptidyl-tyrosine phosphorylation; transferase activity
transferring phosphorus-containing groups; protein binding; non-membrane spanning protein tyrosine kinase activity; nucleus; magnesium ion binding; establishment of cell polarity; microtubule cytoskeleton organization; protein phosphorylation; neuron projection morphogenesis; protein tyrosine kinase activity; ATP binding; protein serine/threonine kinase activity
Homolog in other species WEE1
Omim http://omim.org/entry/193525
Immgen Expression
MEDIAN(HIGH IN B.GC.SP, PROB.FRBC.FL, PREB.FRD.FL, DC8+.TH, TGD.VG5+.ACT.IEL, NK.MCMV1.SP, T.8EFF.SP.OT1.D6.VSVOVA, TGD.TH, T.4SP24-.TH, T.8SP24-.TH, DC.LC.SK)
Gnf Expression
HIGH(HIGHER IN IMM.G1, IMM.G3, AND EMB GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031016
Chromosome 7
Coordinate 110,126,062     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 18
Allele Frequency
A:R0.44
G:V0.56
Amino Acid Change I->V (Isoleucine -> Valine)
Sample ID IGL02884
Median Base Quality 39.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 54 Other Mutations

 Predictions 
Polyphen Score 0.13
Polyphen Prediction Benign

 Availability Details 
Availability Progeny Cryopreserved