Fgd6 - SNV Details



 Gene Information 
Gene Name Fgd6
Old Gene Names for Fgd6 Aa123052 , Etohd4
Gene Description FYVE, RhoGEF and PH domain containing 6 [Source:MGI Symbol;Acc:MGI:1261419]
Uniprot Name
CCDS Name
Gene GO
cytoplasm; metal ion binding; Rho guanyl-nucleotide exchange factor activity; cytoskeleton; cellular_component; regulation of Rho protein signal transduction; regulation of Rho GTPase activity; biological_process; molecular_function
Homolog in other species FGD6
Immgen Expression
MEDIAN(HIGHER IN BCELL GROUP)
Gnf Expression
LOW
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000020021
Chromosome 10
Coordinate 94,045,164     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 22
Allele Frequency
T:R0.41
C:V0.59
Amino Acid Change S->P (Serine -> Proline)
Sample ID IGL02870
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 42 Other Mutations

 Predictions 
Polyphen Score 0.98
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved