Mrc2 - SNV Details



 Gene Information 
Gene Name Mrc2
Gene Description mannose receptor, C type 2 [Source:MGI Symbol;Acc:MGI:107818]
MGI phenotype Homozygous mice are visibly normal, viable and have no reproductive defects. Mouse embryonic fibroblasts derived from null mice exhibit decreased migration while bone marrow-derived macrophages exhibit increased migration.
Uniprot Name
CCDS Name
Gene GO
collagen catabolic process; membrane; protein binding; cell surface; integral component of membrane; carbohydrate binding; plasma membrane; endocytosis; osteoblast differentiation; collagen binding
Homolog in other species MRC2
Omim http://omim.org/entry/612264
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Gnf Expression
MEDIAN(HIGH IN RETINA, PITUITARY, DORSALROOTGANGLION, TRIGEMINAL, KIDNEY, LIVER, C2C12, UMBLICALCORD, NIH.3T3, OSTEOBLASTS, EPITH GROUP, IMM.G2, TRACHEA, PROSTATE, LUNG, BLADDER, UTERUS, OVARY, ADIPOSETISSUE, ADRENALGLAND)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000020695
Chromosome 11
Coordinate 105,333,620     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 29
Allele Frequency
G:R0.62
A:V0.38
Amino Acid Change Disrupted splicing
Splice Position 4
Sample ID IGL02863
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 

 Availability Details 
Availability Progeny Cryopreserved