Arhgap10 - SNV Details



 Gene Information 
Gene Name Arhgap10
Old Gene Names for Arhgap10 A930033b01rik
Gene Description Rho GTPase activating protein 10 [Source:MGI Symbol;Acc:MGI:1925764]
Uniprot Name
CCDS Name
Gene GO
perinuclear region of cytoplasm; cytoskeleton organization; signal transduction; negative regulation of apoptotic process; positive regulation of Rho GTPase activity; intracellular; protein binding; cytosol; Rho GTPase activator activity; plasma membrane
Homolog in other species ARHGAP10
Omim http://omim.org/entry/609746
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, ABT GROUP, TACTIVATION GROUP)
Gnf Expression
MEDIAN(HIGH IN FERTILIZEDEGG, OOCYTE, IMM.G3, OSTEO GROUP, C2C12, UMBLICALCORD, NIH.3T3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037148
Chromosome 8
Coordinate 77,365,100     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 42
Allele Frequency
A:R0.36
T:V0.64
Amino Acid Change L->Q (Leucine -> Glutamine)
Sample ID IGL02834
Median Base Quality 39
Backgrounds C57BL/6
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 27 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved