Vps25 - SNV Details



 Gene Information 
Gene Name Vps25
Old Gene Names for Vps25 1110020n13rik , Aw107467 , D11wsu68e
Gene Description vacuolar protein sorting 25 (yeast) [Source:MGI Symbol;Acc:MGI:106354]
Uniprot Name
CCDS Name
Gene GO
mitochondrion; endosome membrane; regulation of transcription
DNA-templated; protein transport; protein homodimerization activity; protein binding; nucleus; extracellular vesicular exosome; nucleolus; transcription
DNA-templated; molecular_function
Homolog in other species VPS25
Omim http://omim.org/entry/610907
Immgen Expression
HIGH
Gnf Expression
MEDIAN/HIGH(HIGH IN RETINA, PITUITARY, DORSALROOTGANGLION, TRIGEMINAL, KIDNEY, LIVER, IMM.G1, IMM.G3, OSTEO GROUP, C2C12, UMBLICALCORD, NIH.3T3, EPITH GROUP, TRACHEA, LUNG, BLADDER, UTERUS, OVARY, ADIPOSETISSUE, ADRENALGLAND)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000078656
Chromosome 11
Coordinate 101,256,090     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 24
Allele Frequency
A:R0.38
G:V0.62
Amino Acid Change Y->C (Tyrosine -> Cysteine)
Sample ID IGL02795
Median Base Quality 35.5
Backgrounds C57BL/6
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 57 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved