Rasgrp4 - SNV Details



 Gene Information 
Gene Name Rasgrp4
Gene Description RAS guanyl releasing protein 4 [Source:MGI Symbol;Acc:MGI:2386851]
Uniprot Name
CCDS Name
Gene GO
cell differentiation; intracellular signal transduction; membrane; regulation of GTPase activity; regulation of small GTPase mediated signal transduction; cell growth; cytoplasm; cell proliferation; metal ion binding; intracellular; small GTPase mediated signal transduction; guanyl-nucleotide exchange factor activity; nucleus; regulation of Ras GTPase activity; response to extracellular stimulus; plasma membrane; Ras guanyl-nucleotide exchange factor activity; positive regulation of Ras GTPase activity; positive regulation of Ras protein signal transduction
Homolog in other species RASGRP4
Omim http://omim.org/entry/607320
Immgen Expression
MEDIAN
MEDIAN(HIGH IN GN.BM)
Gnf Expression
MEDIAN(HIGH IN MASTCELLS)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000030589
Chromosome 7
Coordinate 29,148,541     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 14
Allele Frequency
T:R0.43
C:V0.57
Amino Acid Change Disrupted splicing
Splice Position 3
Sample ID IGL00594
Median Base Quality 40
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 

 Availability Details 
Availability Progeny Cryopreserved