Ifne - SNV Details



 Gene Information 
Gene Name Ifne
Old Gene Names for Ifne Ifnt1 , Ifne1
Gene Description interferon epsilon [Source:MGI Symbol;Acc:MGI:2667156]
Uniprot Name
CCDS Name
Gene GO
regulation of MHC class I biosynthetic process; humoral immune response; B cell differentiation; defense response; positive regulation of peptidyl-serine phosphorylation of STAT protein; T cell activation involved in immune response; response to exogenous dsRNA; cytokine-mediated signaling pathway; cytokine receptor binding; B cell proliferation; defense response to bacterium; cytokine activity; natural killer cell activation involved in immune response; innate immune response; extracellular region; defense response to virus; type I interferon receptor binding; extracellular space; adaptive immune response
Homolog in other species IFNE
Omim http://omim.org/entry/615223
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000045364
Chromosome 4
Coordinate 88,879,804     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 12
Allele Frequency
T:R0.67
C:V0.33
Amino Acid Change N->D (Asparagine -> Aspartic acid)
Sample ID IGL00594
Median Base Quality 36
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign

 Availability Details 
Availability Progeny Cryopreserved