Gpr64 - SNV Details



 Gene Information 
Gene Name Gpr64
Old Gene Names for Gpr64 Aw212196 , B830041d06rik
Gene Description G protein-coupled receptor 64 [Source:MGI Symbol;Acc:MGI:2446854]
MGI phenotype Hemizygous null male mice display reduced fertility, oligozoospermia, teratozoospermia, asthenozoospermia, abnormal epididymis morphology, and abnormal fluid accumulation resulting in enlarged testes and dilated seminiferous tubules.
Uniprot Name
CCDS Name
Gene GO
membrane; apical plasma membrane; cytoplasm; transmembrane signaling receptor activity; neuropeptide signaling pathway; integral component of membrane; extracellular vesicular exosome; G-protein coupled receptor activity; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; plasma membrane
Homolog in other species GPR64
Omim http://omim.org/entry/300572
Immgen Expression
LOW
Gnf Expression
LOW/MEDIAN(HIGH IN DORSALROOTGANGLION, TRIGEMINAL)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031298
Chromosome X
Coordinate 160,485,777     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 24
Allele Frequency
G:R0.46
A:V0.54
Amino Acid Change V->I (Valine -> Isoleucine)
Sample ID IGL00594
Median Base Quality 39.5
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 
Polyphen Score 0.79
Polyphen Prediction Possibly damaging

 Availability Details 
Availability Progeny Cryopreserved