Fndc3a - SNV Details



 Gene Information 
Gene Name Fndc3a
Old Gene Names for Fndc3a 1700094e19rik , D14ertd453e , F730017h24rik , Fndc3
Gene Description fibronectin type III domain containing 3A [Source:MGI Symbol;Acc:MGI:1196463]
MGI phenotype Males homozygous for an insertional mutation are sterile; females are fertile. In mutant males, spermatids form multinucleated syncytia and fail to mature, while Sertoli cells exhibit abnormal cytoplasmic vacuoles.
Uniprot Name
CCDS Name
Gene GO
Sertoli cell development; membrane; Golgi membrane; fertilization; spermatid development; poly(A) RNA binding; acrosomal vesicle; protein binding; single organismal cell-cell adhesion; integral component of membrane; cytosol; cytoplasmic vesicle; vesicle membrane; Golgi apparatus
Homolog in other species FNDC3A
Immgen Expression
HIGH(HIGHER IN MYELOID GROUP, DC GROUP, TGD GROUP)
Gnf Expression
HIGH(HIGHER IN IMM GROUPS, OESTEO GROUP, EPITH GROUP, BLADDER, UTERUS, OVARY, LUNG, TRACHEA AND ADIPOSETISSUE, PROSTATE, UMBLICALCORD)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000033487
Chromosome 14
Coordinate 72,559,357     (Assembly: GRCm38)    
Ref Base C
Var Base A
Zygosity Heterozygous
Read Depth 17
Allele Frequency
C:R0.53
A:V0.47
Amino Acid Change Disrupted splicing
Splice Position 10
Sample ID IGL00563
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 

 Availability Details 
Availability Progeny Cryopreserved