Gene Name
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Lama2
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Gene Description
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laminin, alpha 2 [Source:MGI Symbol;Acc:MGI:99912]
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MGI phenotype
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Homozygotes for targeted and spontaneous mutations exhibit progressive growth retardation, ataxia, muscle atrophy and degeneration, infertility, and premature lethality. Muscle fiber degeneration is evident as early as the first week of life.
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Uniprot Name
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CCDS Name
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Gene GO
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basement membrane; membrane; regulation of cell migration; sarcolemma; cell adhesion; basal lamina; myelination in peripheral nervous system; regulation of embryonic development; protein binding; extracellular vesicular exosome; vesicle-mediated transport; dendritic spine; extracellular matrix organization; axon guidance; extracellular region; receptor binding; positive regulation of synaptic transmission
cholinergic; laminin-1 complex; regulation of cell adhesion
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Homolog in other species
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LAMA2
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Omim
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http://omim.org/entry/156225
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Immgen Expression
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MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
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Gnf Expression
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LOW/MEDIAN(HIGH IN FERTILIZEDEGG, OOCYTE)
HIGH
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Novel
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Yes
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