Lmtk2 - SNV Details



 Gene Information 
Gene Name Lmtk2
Old Gene Names for Lmtk2 2900041g10rik , A330101p12rik
Gene Description lemur tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:3036247]
Uniprot Name
CCDS Name
Gene GO
protein kinase activity; perinuclear region of cytoplasm; early endosome; protein phosphatase inhibitor activity; nervous system development; protein autophosphorylation; neurotrophin TRK receptor signaling pathway; endocytic recycling; cytoplasm; peptidyl-tyrosine phosphorylation; early endosome to late endosome transport; receptor recycling; transferase activity
transferring phosphorus-containing groups; protein binding; myosin VI binding; peptidyl-threonine phosphorylation; integral component of membrane; peptidyl-serine phosphorylation; transferrin transport; protein phosphorylation; axon guidance; protein tyrosine kinase activity; ATP binding; negative regulation of catalytic activity; recycling endosome; protein serine/threonine kinase activity; Golgi apparatus
Homolog in other species LMTK2
Omim http://omim.org/entry/610989
Immgen Expression
MEDIAN(HIGHER IN MYELOID GROUP, TGD.VG5+.ACT.IEL)
Gnf Expression
MEDIAN/HIGH(LOWER IN PANCREAS, KIDNEY, LIVER, BROWNFAT, SPLEEN, IMM.G2, THYROID, GI GROUP)
MEDIAN(HIGH IN OLFACTORYBULB)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000038970
Chromosome 5
Coordinate 144,134,155     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 52
Allele Frequency
A:R0.48
G:V0.52
Amino Acid Change D->G (Aspartic acid -> Glycine)
Sample ID IGL00427
Median Base Quality 37
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 43 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved