Slc22a26 - SNV Details



 Gene Information 
Gene Name Slc22a26
Old Gene Names for Slc22a26 Bc014805
Gene Description solute carrier family 22 (organic cation transporter), member 26 [Source:MGI Symbol;Acc:MGI:2385316]
Uniprot Name
CCDS Name
Gene GO
integral component of membrane; cellular_component; transmembrane transporter activity; transmembrane transport; biological_process; molecular_function
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000053303
Chromosome 19
Coordinate 7,782,975     (Assembly: GRCm38)    
Ref Base A
Codon Change Tta/Ata
Var Base T
Zygosity Heterozygous
Read Depth 63
Allele Frequency
A:R0.51
T:V0.49
Amino Acid Position 469
Amino Acid Change L->I (Leucine -> Isoleucine)
Sample ID IGL00338
Median Base Quality 38
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 29 Other Mutations

 Predictions 
Polyphen Score 0.18
Polyphen Prediction Benign
Sift Score 0.42
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000064809:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Major facilitator superfamily MFS IPR011701 ENSMUSP00000064809 Pfam 369
530 Description available Search pathways
Major facilitator superfamily domain, general substrate transporter MFS_dom_general_subst_transpt IPR016196 ENSMUSP00000064809 Superfamily 151
525 Description available Search pathways
General substrate transporter Sub_transporter IPR005828 ENSMUSP00000064809 Pfam 100
523 Description available Search pathways
Major facilitator superfamily domain MFS_dom IPR020846 ENSMUSP00000064809 Prosite_profiles 96
520 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved